Posted on 18th Jul 2012
Celadrin is a unique and patented blend of fatty acids that has been shown to support joint function in recent clinical studies. It's been shown to support joint flexibility and mobility and provide reductions in pain for sore joints. Specifically it's been tested in patients with osteoarthritis (OA) and rheumatoid arthritis (RA) and has shown to be of benefit, studies are presented below.
While celadrin is a mix of fatty acids, it's primarily based around one fatty acid ester "Cetyl Myristoleate" otherwise known as CMO. Celadrin also contains other fatty acid esters including cetyl myristate and cetyl oleate. Cetyl Myristoleate was discovered in the early 1960's and was found to provide anti-inflammatory effects and pain relief. Celadrin is the brand name for a patented mix of fatty acid esters, which includes CMO.
Celadrin generally comes in two forms; topical (such as creams and lotions) and oral such as capsule or tablet form. The studies presented below specifically used a lotion or a cream, this currently appears to be the best route, however topical application may not be suitable for those with problems with deeper joint issues (such as hip problems).
As per the clinical studies, applying celadrin cream/lotion to the affected area 2-3 times per day should provide some relief from pain and increase functional activity.
Below 3 studies are presented that have tested topical celadrin in humans and have found benefit. In all 3 studies, pain relief appears to be present. The participants of the studies either had osteo or rheumatoid arthritis.
1. Topical Celadrin's Effects on Knee, Wrist and Elbow Arthritis (Study Here)
This study tested 1 week of topical use celadrin on the knee, elbow and wrist applied twice per day to the affected joint. Participants were divided into 3 groups (knee, wrist and elbow). All participants in the study either had rheumatoid or osteo arthritis and were classes as suffering from moderate to severe pain. A reduction in pain and an improvement in performance was noted in all 3 groups. The knee group in particular saw an improvement in stair climbing ability, the wrist group with a significant improvement in grip endurance.
2. Effect of Celadrin With Confirmed Knee Osteoarthritis (Study Here)
his study tested 40 patients with confirmed osteoarthritis in one or both knees. Participants were divided into two groups, treatment of topical cream twice per day, or placebo. This study was run for 30 days. Participants were tested 3 times. Once at the start (before any application of cream), once 30 minutes after the first application, and once 30 days later.
Authors of the study concluded that celadrin significantly improved knee range of motion and an in functional tests both 30 minutes after first administration and 30 days of daily use. The placebo group did not see improvements. This study is important because it shows us that celadrin can provide quick relief and confirms anecdotal user reports that celadrin acts quickly.
3. Effects of Celadrin Cream On Postural Stability In Patients With Knee Osteoarthritis
This study featured 40 patients with knee osteoarthritis. The goal was to assess standing stability. The study lasted 30 days. Participants were split into 2 groups; one placebo and one applying celadrin cream to the affected area twice per day. After 30 days the researchers concluded that postural stability was improved, the effect is presumed to be though pain relief.
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